发明名称 ALPHA-LIPOIC ACID NANOPARTICLE AND METHOD FOR PRODUCING THE SAME
摘要 <p>Provision of a stable ±-lipoic acid. A method for producing ±-lipoic acid nanoparticles, the method comprising the steps of: preparing an aqueous dispersion liquid containing ±-lipoic acid and a nonionic surfactant; adding a divalent metal salt into the aqueous dispersion liquid, wherein the divalent metal salt is a divalent metal halide, a divalent metal acetate or a divalent metal gluconate; and adding an alkali metal carbonate or an alkali metal phosphate into the aqueous dispersion liquid which has been added with the divalent metal salt, thereby forming ±-lipoic acid nanoparticles.</p>
申请公布号 EP2241314(B1) 申请公布日期 2013.04.17
申请号 EP20080863352 申请日期 2008.12.12
申请人 EZAKI GLICO CO., LTD.;NANOEGG RESEARCH LABORATORIES, INC. 发明人 SUGIMOTO, KAZUHISA;NISHIURA, HIROMI;YAMAGUCHI, YOKO;HIRATA, KEIICHI;KUBOTA, YOSHIKI
分类号 A61K31/385;A61K47/02;A61K47/34;A61P1/02;A61P17/00;A61P39/06;B82Y5/00;C07D339/04 主分类号 A61K31/385
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