发明名称 |
PHARMACEUTICAL COMPOSITIONS COMPRISING TRIGONELLINE AND 4-HYDROXYISOLEUCINE AND A PROCESS THEREOF |
摘要 |
<p>The present invention relates to a pharmaceutical composition having dopaminergic activity and other related pharmaceutical activities comprising trigonelline or its derivative(s) and 4-hydroxyisoleucine or its derivative(s), optionally along with excipients(s); a process of preparing a pharmaceutical composition comprising trigonelline or its derivative(s) and 4-hydroxyisoleucine or its derivative(s), optionally along with excipients(s), wherein the process comprising steps of: (a) extracting a clear solution containing trigonelline and 4-hydroxyisoleucine from plant source; and (b) optionally precipitating derivative(s) of trigonelline and 4-hydroxyisoleucine from the clear solution and obtaining said composition; and an in-vitro method to increase levels of dopamine or to inhibit prolactin by allowing composition comprising trigonelline or its derivative(s) and 4-hydroxyisoleucine or its derivative(s) to bind to cell receptors.</p> |
申请公布号 |
EP2114393(B1) |
申请公布日期 |
2013.04.17 |
申请号 |
EP20080720142 |
申请日期 |
2008.03.03 |
申请人 |
INDUS BIOTECH PRIVATE LIMITED |
发明人 |
BHASKARAN, SUNIL;VISHWARAMAN, MOHAN |
分类号 |
A61K31/198;A61K31/455;A61K36/48;A61K36/74;A61K45/06;A61P25/16 |
主分类号 |
A61K31/198 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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