发明名称 Substituted 1-alkylcinnolin-4(1H)-one derivatives, preparation thereof and therapeutic application of same
摘要 The subject of the present invention is compounds corresponding to the formula (I) in which: X represents a divalent (C2-C5)alkylene radical which is unsubstituted or substituted one or more times by an Alk group; R1 represents a phenyl, a naphthyl, a pyridyl, a 1-benzothienyl or a 1,3-benzodioxolyl; R2 represents a hydrogen atom, a halogen atom, an Alk group, an OAlk group or else a group chosen from —S-Alk, —SO-Alk, —SO2-Alk, —CO—N(R4)-Alk, —N(R4)SO2-Alk, —N(R4)CO-Alk, —N(R4)SO2—N(Alk)2; R3 represents a hydrogen atom, a halogen atom, an Alk group or an OAlk group; R4 represents a hydrogen atom or a (C1-C4)alkyl; Alk represents an unsubstituted or substituted (C1-C4)alkyl. Preparation process and therapeutic application.
申请公布号 US8420651(B2) 申请公布日期 2013.04.16
申请号 US201013262869 申请日期 2010.04.06
申请人 BARBAGALLO ELODIE;LEGEAY CAROLE;RINALDI-CARMONA MURIELLE;ROUX PASCALE;VERNHET CLAUDE;SANOFI 发明人 BARBAGALLO ELODIE;LEGEAY CAROLE;RINALDI-CARMONA MURIELLE;ROUX PASCALE;VERNHET CLAUDE
分类号 A61K31/50;A61K31/501 主分类号 A61K31/50
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