发明名称 |
METHOD AND APPARATUS FOR REDUCING TISSUE DAMAGE AFTER ISCHEMIC INJURY |
摘要 |
A method and apparatus for the local delivery of therapeutic agents reduces myocardial tissue damage due to ischemia. A local delivery device is used for delivery of the therapeutic agents into a coronary artery which feeds the ischemic myocardial tissue. According to one example, an implantable medical device for delivering insulin locally to myocardial tissue includes a therapeutic dosage of insulin in a biocompatible polymer affixed to a stent. The therapeutic dosage of insulin is released from the stent at a therapeutic dosage and over an administration period effective to reduce ischemic injury of the myocardial tissue. |
申请公布号 |
CA2513721(C) |
申请公布日期 |
2013.04.16 |
申请号 |
CA20032513721 |
申请日期 |
2003.11.10 |
申请人 |
CONOR MEDSYSTEMS, INC.;SHANLEY, JOHN F. |
发明人 |
LITVACK, FRANK;PARKER, THEODORE L.;SHANLEY, JOHN F. |
分类号 |
A61L31/16;A61F2/00;A61F2/06;A61F2/84;A61F2/90;A61L29/16;A61L31/10;A61L31/14 |
主分类号 |
A61L31/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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