发明名称 |
Gastrin releasing peptide compounds |
摘要 |
Improved compounds for use in diagnostic imaging or therapy having the formula M-N-O-P-G, wherein M is an optical label or a metal chelator (in the form complexed with a metal radionuclide or not), N-O-P is the linker, and G is the GRP receptor targeting peptide. Methods for imaging a patient and/or providing radiotherapy or phototherapy to a patient using the compounds of the invention are also provided. Methods and kits for preparing a diagnostic imaging agent from the compound are further provided. Methods and kits for preparing a radiotherapeutic agent are further provided. |
申请公布号 |
US8420053(B2) |
申请公布日期 |
2013.04.16 |
申请号 |
US20090551394 |
申请日期 |
2009.08.31 |
申请人 |
CAPPELLETTI ENRICO;LATTUADA LUCIANO;LINDER KAREN E.;MARINELLI EDMUND;NANJAPPAN PALANIAPPA;RAJU NATARAJAN;RAMALINGAM KONDAREDDIAR;SWENSON ROLF E.;TWEEDLE MICHAEL;BRACCO IMAGING S.P.A. |
发明人 |
CAPPELLETTI ENRICO;LATTUADA LUCIANO;LINDER KAREN E.;MARINELLI EDMUND;NANJAPPAN PALANIAPPA;RAJU NATARAJAN;RAMALINGAM KONDAREDDIAR;SWENSON ROLF E.;TWEEDLE MICHAEL |
分类号 |
A61K49/00;A61K51/00;A61K51/08;A61M36/14 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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