发明名称 |
Combined gene therapy for the treatment of macroscopic gliomas |
摘要 |
Described herein are compositions and methods for the treatment of cancer, and particularly brain cancer (e.g., glioma) in a mammal. In various embodiments of the invention, a combined therapeutic approach including TK with systemic ganciclovir administration and Flt3L are used in connection with gene therapeutic techniques or direct peptide injection for the aforementioned indications. Kits useful in practicing the inventive method are also disclosed, as are animal models useful for studying brain cancer.
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申请公布号 |
US8420611(B2) |
申请公布日期 |
2013.04.16 |
申请号 |
US20050572391 |
申请日期 |
2005.08.12 |
申请人 |
LOWENSTEIN PEDRO;CASTRO MARIA;CEDARS-SINAI MEDICAL CENTER |
发明人 |
LOWENSTEIN PEDRO;CASTRO MARIA |
分类号 |
A61K48/00;A01K67/00;A01N63/00 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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