发明名称 |
GENE-EXPRESSION PROFILING WITH REDUCED NUMBERS OF TRANSCRIPT MEASUREMENTS |
摘要 |
The present invention provides compositions and methods for making and using a transcriptome-wide gene-expression profiling platform that measures the expression levels of only a select subset of the total number of transcripts. Because gene expression is believed to be highly correlated, direct measurement of a small number (for example, 1,000) of appropriately-selected transcripts allows the expression levels of the remainder to be inferred. The present invention, therefore, has the potential to reduce the cost and increase the throughput of full-transcriptome gene-expression profiling relative to the well-known conventional approaches that require all transcripts to be measured.
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申请公布号 |
US2013090254(A1) |
申请公布日期 |
2013.04.11 |
申请号 |
US201213646294 |
申请日期 |
2012.10.05 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
LAMB JUSTIN;GOLUB TODD R.;SUBRAMANIAN ARAVIND;PECK DAVID D. |
分类号 |
C12Q1/68;G06F19/20;G06F19/24 |
主分类号 |
C12Q1/68 |
代理机构 |
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地址 |
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