发明名称 ETHYNYL DERIVATIVES
摘要 The present invention relates to ethynyl derivatives of formula I wherein U, V, W, Y, R, R1, R2, R3 and R3′are as described herein. It has been found that the compounds of general formula I are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).
申请公布号 US2013090347(A1) 申请公布日期 2013.04.11
申请号 US201213628128 申请日期 2012.09.27
申请人 HOFFMANN-LA ROCHE INC.;HOFFMANN-LA ROCHE INC. 发明人 JAESCHKE GEORG;LINDEMANN LOTHAR;RICCI ANTONIO;RUEHER DANIEL;STADLER HEINZ;VIEIRA ERIC
分类号 A61K31/44;A61K31/50;A61K31/505;A61P25/00;A61P25/18;C07D213/74;C07D237/20;C07D239/42 主分类号 A61K31/44
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