TREATMENT OF OBESITY AND OBESITY-RELATED DISORDERS BY PHARMACOLOGICAL TARGETING OF KV1.3 POTASSIUM CHANNELS
摘要
<p>Activation of brown adipose tissue, treatment of obesity and/or treatment of obesity-related disorders in human or non-human animal subjects by administering to the subject a potassium channel inhibiting agent. The potassium channel inhibiting agent may comprise ShK toxin or a modified ShK toxin. Examples of modified ShK toxins include ShK-186.</p>
申请公布号
CA2850357(A1)
申请公布日期
2013.04.11
申请号
CA20122850357
申请日期
2012.10.02
申请人
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;KINETA ONE, LLC
发明人
CHANDY, GEORGE K.;UPADHAYAY, SANJEEV KUMAR;WANG, PING H.;CORSI, PAOLO SASSONE;MAHAN, KRISTIN LYNN-ECKEL;IADONATO, SHAWN;MUKERGEE, JOSEPH;MIRBOLOOKI, REZA M.
