CRYSTALLINE FORMS OF TIGECYCLINE AND METHOD FOR PREPARING THEM

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to a crystalline form of tigecycline I characterised by the fact that an X-ray picture formed by powder X-ray diffraction shows diffraction peaks at the angles of 2? 5.2° and 11.1°, as well as a diffraction peak at the angle of 29 8.3° and a diffraction peak at the angle of 2? 24.8°. The crystalline form of tigecycline I is used for preparing pharmaceutical formulations, for treating bacterial diseases.EFFECT: preparing the solid crystalline form of tigecycline possessing the improved stability characteristics.8 cl, 9 dwg, 4 tbl, 10 ex