发明名称 NOVEL DERIVATIVES OF MESALAZINE, PROCESS OF THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF INTESTINAL INFLAMMATORY DISEASES
摘要 The present invention refers to the compounds corresponding to the following general formulas (I) and (Ia): wherein: R═C4-C8 alkanoyl; and X═NH—R1 where R1═H, or an amine protecting group; and/or the pharmaceutically acceptable salts thereof. A further object of the present invention is represented by the use of the compounds of formula (Ia), in particular 5-amino-2-(butyryloxy)benzoic acid and/or pharmaceutically acceptable salts thereof, as a medicament and by the use thereof for the treatment of intestinal inflammatory diseases.
申请公布号 EP2576495(A1) 申请公布日期 2013.04.10
申请号 EP20110729709 申请日期 2011.05.18
申请人 SOFAR SPA 发明人 LABRUZZO, CARLA
分类号 C07C205/60;C07C229/64;C07C271/28 主分类号 C07C205/60
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