发明名称 A METHOD FOR THE N-DEMETHYLATION OF N-METHYL HETEROCYCLES
摘要 The present invention provides methods of N-demethylating, N-methylated heterocycles and N-methyl, N-oxide heterocycles using a transition metal with an oxidation state of zero, ferrocene or substituted derivatives thereof, or Cr3+. N-demethylated heterocycles prepared by the methods of the present invention are also provided.
申请公布号 EP2477984(A4) 申请公布日期 2013.04.10
申请号 EP20100816472 申请日期 2010.09.16
申请人 MONASH UNIVERSITY 发明人 SCAMMELLS, PETER JOHN;ORBELL, GAIK
分类号 C07B37/06;A61K31/485;C07D451/06;C07D451/10;C07D489/02;C07D489/08 主分类号 C07B37/06
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