发明名称 |
A METHOD FOR THE N-DEMETHYLATION OF N-METHYL HETEROCYCLES |
摘要 |
The present invention provides methods of N-demethylating, N-methylated heterocycles and N-methyl, N-oxide heterocycles using a transition metal with an oxidation state of zero, ferrocene or substituted derivatives thereof, or Cr3+. N-demethylated heterocycles prepared by the methods of the present invention are also provided. |
申请公布号 |
EP2477984(A4) |
申请公布日期 |
2013.04.10 |
申请号 |
EP20100816472 |
申请日期 |
2010.09.16 |
申请人 |
MONASH UNIVERSITY |
发明人 |
SCAMMELLS, PETER JOHN;ORBELL, GAIK |
分类号 |
C07B37/06;A61K31/485;C07D451/06;C07D451/10;C07D489/02;C07D489/08 |
主分类号 |
C07B37/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|