The present invention concerns methods and compositions for treating or assessing treatment of diseases related to mis-expression of genes or genetic pathways that can be modulated by let-7. Methods may include evaluating patients for genes or genetic pathways modulated by let-7, and/or using an expression profile to assess the condition of a patient or treating the patient with an appropriate miRNA.
申请公布号
EP2104737(B1)
申请公布日期
2013.04.10
申请号
EP20070871693
申请日期
2007.12.10
申请人
ASURAGEN, INC.;YALE UNIVERSITY, INC.
发明人
JOHNSON, CHARLES D.;BYROM, MIKE;BADER, ANDREAS G.;SLACK, FRANK J.;BROWN, DAVID;OVCHARENKO, DMITRIY;KELNAR, KEVIN
