| 发明名称 |
IMPROVED PROCESS FOR THE PREPARATION OF PROPENAL INTERMEDIATE AND DERIVATIVES THEREOF |
| 摘要 |
<p>The present invention provides an improved process for the preparation of (E)-N-(4-(4-fluorophenyl)-6-isopropyl-5-(3-oxoprop-1-enyl)pyrimidin-2-yl)-N-methyl methanesulfon-amide, which is a useful intermediate for the preparation of (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl methylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxy hept-6-enoic acid, commonly known as Rosuvastatin.</p> |
| 申请公布号 |
EP2576518(A1) |
申请公布日期 |
2013.04.10 |
| 申请号 |
EP20100726900 |
申请日期 |
2010.06.07 |
| 申请人 |
PHARMATHEN S.A. |
发明人 |
KOFTIS, THEOHARIS, V;ANDREOU, THANOS;MENISIOU, ARISTOTELIS;NEOKOSMIDIS, EFSTRATIOS;ZITROU, ASTERIA |
| 分类号 |
C07D239/42 |
主分类号 |
C07D239/42 |
| 代理机构 |
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