| 摘要 |
<p>The present invention relates to the in vitro and ex vivo culture of leukemia initiating cells (LICs). This has utility in various applications, such as screening for candidate agents for treating leukemia, identifying leukemia patients likely to respond to a candidate agent for treating leukemia, monitoring a leukemia patient for drug resistance, e.g. chemoresistance, to an agent, predicting the prognosis of a leukemia patient and determining the ability of a therapeutic agent to reduce the proportion of LICs in a leukemic patient.</p> |
