| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to new N-aryl-2,3-diaroyl-8,10-dimethylpyrido[2',3':3,4]pyrazolo[1,5-?]pyrimidine-4-carboxamides of formula I possessing analgesic activity, and to a method for preparing them. In formula IAr=Ph, CHMe-4, CHOMe-4; Ar-Ph, CHMe-4, CH(Me)-2,5. The method for preparing said compounds consists in a reaction of 1-aryl-4,5-diaroyl-1H-pyrrol-2,3-diones with 3-amino-4,6-dimethyl-2H-pyrazolo[3,4-6]pyridine at temperature 108-110°C in an absolute toluene medium.EFFECT: there are prepared the compounds possessing analgesic activity.4 cl, 1 dwg, 1 tbl, 3 ex |
