| 发明名称 |
HIGH-AFFINITY NUCLEIC ACID APTAMERS AGAINST SCLEROSTIN PROTEIN |
| 摘要 |
<p>Described are nucleic acid aptamers that are able to bind to and inhibit the function of sclerostin, which is an important negative regulator of bone growth. The aptamers have application as therapeutics for diseases of bone including osteoporosis, osteopenia, osteoarthritis and other osteoporosis-related conditions and complications.</p> |
| 申请公布号 |
EP2576786(A1) |
申请公布日期 |
2013.04.10 |
| 申请号 |
EP20110785965 |
申请日期 |
2011.05.23 |
| 申请人 |
THE UNIVERSITY OF HONG KONG |
发明人 |
TANNER, JULIAN ALEXANDER;SHUM, KATO;CHAN, SZELAI, CELINE |
| 分类号 |
C12N15/115;A61K31/711;A61K31/7125;A61P19/08;A61P19/10 |
主分类号 |
C12N15/115 |
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