COMPOSITIONS AND METHODS FOR T-CELL ACTIVATION COMPRISING GM-CSF AND TUMOR ANTIGEN FUSION PROTEINS

摘要

Disclosed are therapeutic compositions and methods for inducing cytotoxic T
cell responses in vitro and in vivo. The therapeutic compositions consist of
antigen presenting cells activated by contact with a polypeptide complex
constructed by joining together a dendritic cell-binding protein and a
polypeptide antigen. Also disclosed are expression vectors and systems for
producing the polypeptide complexes.