发明名称 Pyridines
摘要 The present invention is concerned with isoxazole-pyridines of formula I, having affinity and selectivity for GABA A α5 receptor, their manufacture, pharmaceutical compositions containing them and their use as pharmaceuticals. The active compounds of the present invention are useful as cognitive enhancer or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease.
申请公布号 US8415379(B2) 申请公布日期 2013.04.09
申请号 US20100768762 申请日期 2010.04.28
申请人 JAKOB-ROETNE ROLAND;LUCAS MATTHEW C.;THOMAS ANDREW;HOFFMANN-LA ROCHE INC.;ROCHE PALO ALTO LLC 发明人 JAKOB-ROETNE ROLAND;LUCAS MATTHEW C.;THOMAS ANDREW
分类号 A61K31/443;C07D413/14 主分类号 A61K31/443
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