发明名称 Pyrimidinylpiperidinyloxypyridinone analogues as GPR119 modulators
摘要 Novel compounds of structure Formula I: or an enantiomer, a diastereomer, or a pharmaceutically acceptable salt thereof, wherein n1, R1, R2, R3 and R4 are defined herein, are provided which are GPR119 G protein-coupled receptor modulators. GPR119 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring GPR119 G protein-coupled receptor modulator therapy. Thus, the disclosure also concerns compositions comprising these novel compounds and methods of treating diseases or conditions related to the activity of the GPR119 G protein-coupled receptor by using any of these novel compounds or a composition comprising any of such novel compounds.
申请公布号 US8415367(B2) 申请公布日期 2013.04.09
申请号 US201113080758 申请日期 2011.04.06
申请人 WACKER DEAN;O'CONNOR STEPHEN;HONG ZHENQIU;BRISTOL-MYERS SQUIBB COMPANY 发明人 WACKER DEAN;O'CONNOR STEPHEN;HONG ZHENQIU
分类号 A01N43/54;A61K31/505 主分类号 A01N43/54
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