发明名称 |
Pharmaceutical composition containing irbesartan |
摘要 |
This invention relates to pharmaceutical compositions containing irbesartan, providing oral formulations with a high relative amount or concentration of irbesartan. In one embodiment, the present invention provides an oral formulation of irbesartan containing greater than 70% w/w irbesartan. In another embodiment, the invention provides an oral formulation of irbesartan which exhibits a dissolution profile according to which greater than about 85% of the Irbesartan is dissolved within about 30 minutes using USP apparatus 2, placing the tablet in 1000 mL of 0.1N hydrochloric acid at 37° C. with paddle speed of 50 rpm. The formulation can optionally contain at least one additional active ingredient. |
申请公布号 |
US8414920(B2) |
申请公布日期 |
2013.04.09 |
申请号 |
US201213485493 |
申请日期 |
2012.05.31 |
申请人 |
KOLATKAR GERSHON;ZISMAN ERELA;TEVA PHARMACEUTICAL INDUSTRIES LTD. |
发明人 |
KOLATKAR GERSHON;ZISMAN ERELA |
分类号 |
A61K9/20;A61K31/4184;A61K31/54;B08B6/00 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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