发明名称 |
Sparc and methods of use thereof |
摘要 |
The invention provides methods for predicting or determining the response of a mammalian tumor to a chemotherapeutic agent and for treating a mammalian tumor comprising detecting and quantifying the SPARC protein or RNA in a sample isolated from the mammal. The invention further provides kit for predicting the response of a mammalian tumor to a chemotherapeutic agent, comprising a means for the isolation of protein or RNA from the tumor, a SPARC protein or RNA detection and quantification means, control RNAs, and rules for predicting the response of the tumor based on the level of SPARC protein or RNA in tumor.
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申请公布号 |
US8415304(B2) |
申请公布日期 |
2013.04.09 |
申请号 |
US20070295068 |
申请日期 |
2007.03.29 |
申请人 |
TRIEU VUONG;DESAI NEIL P.;SOON-SHIONG PATRICK;ABRAXIS BIOSCIENCE, LLC |
发明人 |
TRIEU VUONG;DESAI NEIL P.;SOON-SHIONG PATRICK |
分类号 |
A01N61/00;A61K31/00;A61K38/00;A61K49/00;C12Q1/00;G01N1/00;G01N33/48;G01N33/53;G01N33/567;G01N33/574 |
主分类号 |
A01N61/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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