发明名称 |
Inhibitor of plasminogen activator inhibitor-1 |
摘要 |
The present invention relates to a novel compound having plasminogen activator inhibitor-1 (PAI-1) inhibitory activity, and a PAI-1 inhibitor comprising the compound as an active ingredient. The present invention further relates to a pharmaceutical composition that has an inhibitory action on PAI-1 activity and is useful in the prevention and treatment of various diseases whose onset is associated with PAI-1 activity. The novel compound is represented by the following general formula. Each symbol is defined as those in the specification. |
申请公布号 |
US8415479(B2) |
申请公布日期 |
2013.04.09 |
申请号 |
US20090935609 |
申请日期 |
2009.03.31 |
申请人 |
MIYATA TOSHIO;YAMAOKA NAGAHISA;KODAMA HIDEHIKO;MURANO KENJI;RENASCIENCE CO., LTD. |
发明人 |
MIYATA TOSHIO;YAMAOKA NAGAHISA;KODAMA HIDEHIKO;MURANO KENJI |
分类号 |
C07D213/00;A61K31/44 |
主分类号 |
C07D213/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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