| 发明名称 |
STABLE FORMULATIONS OF THIADIAZOLE DERIVATIIVE |
| 摘要 |
<p num="1"><br/><br/><br/>The present invention provides formulation parameters and manufacturing <br/>conditions for stable pharmaceutical <br/>compositions comprising N-{4-(2,2-dimethyl-propionyl)-(5R)-5-[(2-ethylamino-<br/>ethanesulfonylamino)-methyl]-5-phenyl-4,5-dihy-dro-[1,3,4]thiadiazol-2-yl}-2,2-<br/>dimeth yl-propionamide <br/>that minimize undesirable chiral conversion to the less active S enantiomeric <br/>form.<br/>
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| 申请公布号 |
CA2694277(C) |
申请公布日期 |
2013.04.09 |
| 申请号 |
CA20082694277 |
申请日期 |
2008.07.07 |
| 申请人 |
ELI LILLY AND COMPANY;KYOWA HAKKO KIRIN CO., LTD. |
发明人 |
KUSANO, HIROKO;MISHRA, DINESH SHYAMDEO;TASHIRO, YOSHIKAZU;WATANABE, YOSUKE;ZHUANG, HONG |
| 分类号 |
A61K9/19;A61K31/433 |
主分类号 |
A61K9/19 |
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