发明名称 PHARMACEUTICAL COMPOSITIONS OF N-METHYL-2-[3-((E)-2-PYRIDIN-2-YL-VINYL)-1H-INDAZOL-6-YLSULFANYL]-BENZAMIDE
摘要 The present invention relates to pharmaceutical compositions containing axitinib, which is known as N-methyl-2-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]- benzamide or 6-[2-(methylcarbamoyl)phenylsulfanyl]-3-E-[2-(pyridin-2- yl)ethenyl]indazole, or crystalline forms thereof, that protect axitinib from degradation, including photodegradation, as well as the therapeutic use of such compositions. The present invention also relates to novel photodegradants of axitinib.
申请公布号 CA2847860(A1) 申请公布日期 2013.04.04
申请号 CA20122847860 申请日期 2012.09.26
申请人 PFIZER INC. 发明人 GIERER, DANIEL SCOTT;MORGADO, JAMES ERIC;MURPHY, BRENDAN JOHN;SIMMONS, DARYL MICHAEL
分类号 A61K9/28;A61K31/4439 主分类号 A61K9/28
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