发明名称 METHOD AND COMPOSITION FOR TARGETING GC1QR/P32
摘要 <P>PROBLEM TO BE SOLVED: To provide molecules that selectively interact with gC1qR/p32, and are suitable for selectively targeting chemotherapeutic drugs, gene therapy vectors or other agents to the appropriate tissue. <P>SOLUTION: Methods of treating a disease associated with gC1q/p32 receptor are disclosed in the specification. The methods comprise a step of identifying a subject having a disease associated with the gC1q/p32 receptor, and a step of administering to the subject a composition comprising SEQ ID NO: 1. Methods of detecting the presence of gC1q/p32 receptor are further disclosed. The methods comprises a step of bringing into contact a cell and a Lyp-1 composition, wherein the Lyp-1 composition comprises a moiety linked to a composition comprising SEQ ID NO: 1, and a step of detecting interaction between the gC1q/p32 receptor and the Lyp-1 composition, thereby detecting the presence of gC1q/p32 receptor. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013060463(A) 申请公布日期 2013.04.04
申请号 JP20120282110 申请日期 2012.12.26
申请人 BURNHAM INST FOR MEDICAL RESEARCH 发明人 RUOSLAHTI ERKKI;FOGAL VALENTINA
分类号 A61K38/00;A61K31/136;A61K31/196;A61K31/198;A61K31/395;A61K31/407;A61K31/519;A61K31/704;A61K31/7048;A61K31/7105;A61K33/24;A61K39/395;A61K45/00;A61P35/00;A61P43/00;C12N15/09;C12Q1/02;C12Q1/70;G01N33/15;G01N33/50;G01N33/68 主分类号 A61K38/00
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