EPIGENETIC CO-REPRESSORS OF THE GAMMA-GLOBIN GENE AND METHODS OF USING SAME
摘要
<p>This disclosure describes methods of screening for compounds that disrupt the interaction between DNMT1 and the gamma-globin promoter or between LSD-1 and the gamma-globin promoter. This disclosure describes methods of screening for compounds that de-repress the gamma-globin gene.</p>
申请公布号
WO2012162514(A3)
申请公布日期
2013.04.04
申请号
WO2012US39368
申请日期
2012.05.24
申请人
REGENTS OF THE UNIVERSITY OF MICHIGAN;ENGEL, JAMES DOUGLAS;TANABE, OSAMU;SHI, LIHONG