SFLT1 IN SUBJECTS DURING OR IMMEDIATELY AFTER PHYSICAL EXERCISE

摘要

The present invention relates to a method for diagnosing in a subject who participates in exercise and who exhibits chest pain whether chest pain is associated with cardiac ischemia, or not. The method is based on the determination of the amount of soluble fms-like tyrosine kinase-1 (sFlt1 ) in a sample from said subject obtained during or immediately after physical exercise, and on the comparison of the thus determined amount of sFlt1 to a reference amount. In the context of the method of the present invention, the reference amount shall be derived from a sample from a reference subject obtained during or immediately after physical exercise, or from a group thereof. The present invention also relates to a system for diagnosing in a subject who participates in exercise and who exhibits chest pain whether chest pain is associated with cardiac ischemia and to reagents and kits used in performing the methods disclosed herein.