发明名称 |
Imidazole Derivatives |
摘要 |
The present application provides novel imidazole compounds and pharmaceutically acceptable salts thereof. Also provided are methods for preparing these compounds. These compounds are useful in inhibiting CYP17 activity by administering a therapeutically effective amount of one or more of the compounds to a patient. By doing so, these compounds are effective in treating conditions associated with CPY17 activity. A variety of conditions can be treated using these compounds and include diseases which are characterized by abnormal cellular proliferation. In one embodiment, the disease is cancer, such as prostate cancer.
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申请公布号 |
US2013085164(A1) |
申请公布日期 |
2013.04.04 |
申请号 |
US201213632007 |
申请日期 |
2012.09.30 |
申请人 |
ENDO PHARMACEUTICALS INC.;ENDO PHARMACEUTICALS INC. |
发明人 |
SMITH ROGER ASTBURY;LAPING NICHOLAS JAMES;VENKATESAN ARANAPAKAM;THOMPSON SCOTT KEVIN;KETHIRI RAGHAVA REDDY;SIVANANDHAN DHANALAKSHMI;VENKATESHAPPA CHANDREGOWDA;KULKARNI BHEEMASHANKAR;DEWANG PURUSHOTTAM;KRISTAM RAJENDRA;KASIBHATLA SRINIVAS;DEVRAJ RAJESH |
分类号 |
A61K31/4178;A61K31/427;A61K31/433;A61K31/4439;A61P35/00;C07D401/06;C07D405/14;C07D409/06;C07D409/14;C07D417/06;C07D417/14 |
主分类号 |
A61K31/4178 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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