发明名称 Imidazole Derivatives
摘要 The present application provides novel imidazole compounds and pharmaceutically acceptable salts thereof. Also provided are methods for preparing these compounds. These compounds are useful in inhibiting CYP17 activity by administering a therapeutically effective amount of one or more of the compounds to a patient. By doing so, these compounds are effective in treating conditions associated with CPY17 activity. A variety of conditions can be treated using these compounds and include diseases which are characterized by abnormal cellular proliferation. In one embodiment, the disease is cancer, such as prostate cancer.
申请公布号 US2013085164(A1) 申请公布日期 2013.04.04
申请号 US201213632007 申请日期 2012.09.30
申请人 ENDO PHARMACEUTICALS INC.;ENDO PHARMACEUTICALS INC. 发明人 SMITH ROGER ASTBURY;LAPING NICHOLAS JAMES;VENKATESAN ARANAPAKAM;THOMPSON SCOTT KEVIN;KETHIRI RAGHAVA REDDY;SIVANANDHAN DHANALAKSHMI;VENKATESHAPPA CHANDREGOWDA;KULKARNI BHEEMASHANKAR;DEWANG PURUSHOTTAM;KRISTAM RAJENDRA;KASIBHATLA SRINIVAS;DEVRAJ RAJESH
分类号 A61K31/4178;A61K31/427;A61K31/433;A61K31/4439;A61P35/00;C07D401/06;C07D405/14;C07D409/06;C07D409/14;C07D417/06;C07D417/14 主分类号 A61K31/4178
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