Immunogenic compositions

摘要

The invention provides an immunogenic composition comprising: a) a conjugate that is a capsular saccharide from GBS serotype la conjugated to a carrier protein; b) a conjugate that is a capsular saccharide from GBS serotype lb conjugated to a carrier protein; and c) a conjugate that is a capsular saccharide from GBS serotype III conjugated to a carrier protein. The invention also provides a method for immunising a patient against infection by GBS comprising the step of administering to the patient a conjugate that is a capsular saccharide from GBS conjugated to a diphtheria toxoid or derivative thereof, wherein the patient has been pre-immunised with a diphtheria toxoid or derivative thereof.