发明名称 |
siRNA against CCL22 for treatment of atopy dermatitis and composition of therapeutic agent comprising the same |
摘要 |
PURPOSE: A siRNA with effect of treating atopic dermatitis and a composition containing the same are provided to suppress IL-4 expression and to increase IFN-gamma. CONSTITUTION: A composition for treating atopic dermatitis contains siRNA which is specific to a target sequence of CCL22 gene as an active ingredient. The siRNA has a base sequence of sequence number 2. A composition for treating atopic dermatitis contains bacterial cells transformed by a recombinant vector containing a gene which transcribes the siRNA. The bacterial cell is Salmonella typhimurium. The recombinant vector is pcDNA-CCL22miRNA. |
申请公布号 |
KR101250031(B1) |
申请公布日期 |
2013.04.03 |
申请号 |
KR20100093908 |
申请日期 |
2010.09.28 |
申请人 |
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发明人 |
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分类号 |
A61K31/7105;A61K35/74;A61K38/16;A61P17/00 |
主分类号 |
A61K31/7105 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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