发明名称 |
LONG-ACTING COAGULATION FACTORS AND METHODS OF PRODUCING SAME |
摘要 |
Polypeptides and polynucleotides encoding same comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotrophin attached to a carboxy terminus of a coagulation factor and not to an amino terminus are disclosed. Pharmaceutical compositions comprising the polypeptides and polynucleotides of the invention and methods of using same are also disclosed. |
申请公布号 |
EP2451473(A4) |
申请公布日期 |
2013.04.03 |
申请号 |
EP20100796803 |
申请日期 |
2010.07.01 |
申请人 |
PROLOR BIOTECH INC. |
发明人 |
FIMA, UDI EYAL;HART, GILI |
分类号 |
A61K38/36;A61P7/02;C07H21/04;C07K14/745;C12N5/10;C12N15/63 |
主分类号 |
A61K38/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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