The invention provides small molecule mimics of the Smac peptide that are dimers or dimer-like compounds having two binding domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
申请公布号
EP2493879(A4)
申请公布日期
2013.04.03
申请号
EP20100830467
申请日期
2010.10.28
申请人
JOYANT PHARMACEUTICALS, INC.
发明人
SUN, HAIZHOU;XU, XIAOMING;ZHOU, MING;HARRAN, SUSAN;HANSON, GUNNAR, JAMES
