发明名称 |
Stabilized activin IIB receptor polypeptides and uses thereof |
摘要 |
The present invention provides stabilized activin IIB receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the stabilized polypeptides and proteins. Compositions and methods for treating muscle-wasting diseases and metabolic disorders are also provided.
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申请公布号 |
US8410043(B2) |
申请公布日期 |
2013.04.02 |
申请号 |
US20090626375 |
申请日期 |
2009.11.25 |
申请人 |
SUN JEONGHOON;TAM LEI-TING TONY;MICHAELS MARK LEO;BOONE THOMAS C.;DESHPANDE ROHINI;LI YUE-SHENG;HAN HQ;ATARA BIOTHERAPEUTICS, INC. |
发明人 |
SUN JEONGHOON;TAM LEI-TING TONY;MICHAELS MARK LEO;BOONE THOMAS C.;DESHPANDE ROHINI;LI YUE-SHENG;HAN HQ |
分类号 |
A61K38/00;A61K38/18 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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地址 |
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