发明名称 Trypsin-like serine protease inhibitors, and their preparation and use
摘要 The invention relates to inhibitors of trypsin-like serine proteases of the general formula (I) which, as well as plasmin, also inhibit plasma kallikrein, and to their preparation and use as medicaments, preferably for treatment of blood loss, especially in the case of hyperfibrinolytic states, in organ transplants or heart surgery interventions, in particular with a cardiopulmonary bypass, or as a constituent of a fibrin adhesive.
申请公布号 US8410310(B2) 申请公布日期 2013.04.02
申请号 US201213471007 申请日期 2012.05.14
申请人 STEINMETZER TORSTEN;SCHWEINITZ ANDREA;STUERZEBECHER JOERG;STEINMETZER PETER;SOEFFING ANETT;VAN DE LOCHT ANDREAS;NICKLISCH SILKE;REICHELT CLAUDIA;LUDWIG FRIEDRICH-ALEXANDER;SCHULZE ALEXANDER;DAGHISH MOHAMMED;HEINICKE JOCHEN;THE MEDICINES COMPANY (LEIPZIG) GMBH 发明人 STEINMETZER TORSTEN;SCHWEINITZ ANDREA;STUERZEBECHER JOERG;STEINMETZER PETER;SOEFFING ANETT;VAN DE LOCHT ANDREAS;NICKLISCH SILKE;REICHELT CLAUDIA;LUDWIG FRIEDRICH-ALEXANDER;SCHULZE ALEXANDER;DAGHISH MOHAMMED;HEINICKE JOCHEN
分类号 C07D303/00 主分类号 C07D303/00
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