发明名称 9-(piperazinylalkyl) carbazoles as Bax-modulators
摘要 Piperazine compounds for use as pharmaceutically active compounds and in pharmaceutical formulations that are useful for the treatment of disorders associated with apoptosis, including neurodegenerative disorders, diseases associated with polyglutamine tracts, epilepsy, ischemia, infertility, cardiovascular disorders, renal hypoxia, hepatitis and AIDS, where the piperazine compounds are represented by formula (I) and the terms R0, R1, R2, R3, k, l, m, n, and X are defined herein:
申请公布号 US8410110(B2) 申请公布日期 2013.04.02
申请号 US201113225760 申请日期 2011.09.06
申请人 HALAZY SERGE;CHURCH DENNIS;ANTONSSON BRUNO;BOMBRUN AGNES;GERBER PATRICK;MARTINOU JEAN-CLAUDE;MERCK SERONO SA 发明人 HALAZY SERGE;CHURCH DENNIS;ANTONSSON BRUNO;BOMBRUN AGNES;GERBER PATRICK;MARTINOU JEAN-CLAUDE
分类号 A61K31/497;C07D401/12;A61K31/495;A61K31/496;A61K31/5377;A61P1/00;A61P1/16;A61P9/00;A61P9/04;A61P9/10;A61P11/06;A61P13/12;A61P15/08;A61P25/00;A61P25/08;A61P25/14;A61P25/16;A61P25/28;A61P27/02;A61P29/00;A61P31/04;A61P31/18;A61P37/06;A61P43/00;C07D209/86;C07D209/88;C07D403/06;C07D405/12;C07D407/14;C07D409/04;C07D409/12;C07D413/12;C07D417/12;C07D417/14 主分类号 A61K31/497
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