发明名称 Oligoribonucleotide inhibitors of Nrf2 and methods of use thereof for treatment of cancer
摘要 The invention provides novel double stranded oligoribonucleotides that inhibit the Nrf2 gene. The invention also provides a pharmaceutical composition comprising one or more such oligoribonucleotides, and a vector capable of expressing the oligoribonucleotide. The present invention also relates to methods and compositions for treating or preventing the incidence or severity of a cancerous disease, particularly various lung cancers.
申请公布号 US8410069(B2) 申请公布日期 2013.04.02
申请号 US20100901207 申请日期 2010.10.08
申请人 FEINSTEIN ELENA;QUARK PHARMACEUTICALS, INC. 发明人 FEINSTEIN ELENA
分类号 C12N15/11;C07H21/02 主分类号 C12N15/11
代理机构 代理人
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