SUBSTITUTED AZEPINE DERIVATIVES AS SEROTONIN RECEPTOR MODULATORS

摘要

The present invention generally relates to a series of compounds, to
pharmaceutical compositions containing the compounds, and to use of the
compounds and compositions as therapeutic agents. More specifically,
compounds of the present invention are hexahydroazepinoindole and
octahydroazepinoindole compounds. These compounds are serotonin receptor
(5--HT) ligands and are useful for treating diseases, disorders, and
conditions wherein
modulation of the activity of serotonin receptors (5-HT) is desired (e.g.
anxiety,
depression and obesity). Compounds of the following formula are provided:

(see above formula)