PHARMACEUTICAL COMPOSITION COMPRISING PRNP GENE USING RECOMBINANT ADENOVIRUS VECTOR FOR PREVENTING OR TREATING PRION DISEASE

摘要

PURPOSE: A transfection system of Prnp genes using a recombinant adenovirus vector is provided to suppress PrP^Sc-mediated neural cell apoptosis, to protect nerve cells, and to prevent or treat prion disease. CONSTITUTION: A pharmaceutical composition for preventing or treating prion disease contains Prnp genes using a recombinant adenovirus vector as an active ingredient. The prion disease is related to PrP^Sc-mediated neural cell apoptosis.