发明名称 |
Methods and compositions for prevention or treatment of RSV infection |
摘要 |
Methods and compositions are provided for the prevention or treatment of RSV infection in a human. The methods include administering one or more doses of a composition comprising an siRNA. The dose can be formulated for topical or parenteral administration. Topical administration includes administration as a nasal spray, or by inhalation of respirable particles or droplets. The siRNA comprises a sense strand of ALN-RSV01 and an antisense strand of ALN-RSV01. |
申请公布号 |
US8410073(B2) |
申请公布日期 |
2013.04.02 |
申请号 |
US201213359421 |
申请日期 |
2012.01.26 |
申请人 |
VAISHNAW AKSHAY;NOCHUR SARASWATHY V.;ELBASHIR SAYDA;MANOHARAN MUTHIAH;MEYERS RACHEL;ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
VAISHNAW AKSHAY;NOCHUR SARASWATHY V.;ELBASHIR SAYDA;MANOHARAN MUTHIAH;MEYERS RACHEL |
分类号 |
A61K31/70;C07H21/02;C07H21/04;C12Q1/68 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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