发明名称 |
HIGH AFFINITY BINDING SITE OF HGFR AND METHODS FOR IDENTIFICATION OF ANTAGONISTS THEREOF |
摘要 |
Use of a polynucleotide encoding at least the extra-cellular IPT-3 and IPT-4 domains of hepatocyte growth factor receptor or a polypeptide comprising at least the extra-cellular IPT-3 and IPT-4 domains of hepatocyte growth factor receptor for the screening and/or development of pharmacologically active agents useful in the treatment of cancer, preferably a cancer with dysregulation of hepatocyte growth factor receptor. |
申请公布号 |
EA017863(B1) |
申请公布日期 |
2013.03.29 |
申请号 |
EA20090000537 |
申请日期 |
2009.05.13 |
申请人 |
METHERESIS TRANSLATIONAL RESEARCH SA |
发明人 |
COMOGLIO PAOLO, MARIA;CARMINATI PAOLO;MICHIELI PAOLO;BASILICO CRISTINA |
分类号 |
C12Q1/25;A61K38/00;A61K48/00;C12N9/12;C12P21/02 |
主分类号 |
C12Q1/25 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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