| 发明名称 |
PROCESS FOR PREPARING AN INTERMEDIATE TO MU OPIOID RECEPTOR ANTAGONISTS |
| 摘要 |
The invention provides an efficient method for preparing 3-endo-(8-azabicyclo[3.2.1]oct-3-yl)benzamide by hydrogenation, under controlled conditions, of an amino-protected 3-(8-azabicyclo[3.2.1]oct-2-en-3-yl)benzamide intermediate in which the amino-protecting group is removable by catalytic hydrogenation. |
| 申请公布号 |
US2013079523(A1) |
申请公布日期 |
2013.03.28 |
| 申请号 |
US201213551774 |
申请日期 |
2012.07.18 |
| 申请人 |
COLSON PIERRE-JEAN;YU YING;LONG DANIEL D.;STERGIADES IOANNA;THERAVANCE, INC. |
发明人 |
COLSON PIERRE-JEAN;YU YING;LONG DANIEL D.;STERGIADES IOANNA |
| 分类号 |
C07D451/06 |
主分类号 |
C07D451/06 |
| 代理机构 |
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