发明名称 |
FUSION PROTEIN FOR SUPPRESSING CANCER CELL GROWTH AND SUPPRESSING VASCULOGENESIS, AND ANTICANCER COMPOSITION COMPRISING SAME |
摘要 |
The present invention relates to a fusion protein resulting from the bonding of a cancer-specific antibody and a vasculogenesis suppressing agent, and relates to a composition for treating cancer comprising same. More specifically, in the present invention it is preferable that the cancer-specific antibody is trastuzumab or a fragment thereof, and the vasculogenesis suppressing agent is a VEGF-Trap. When the fusion protein according to the present invention is used, there are advantages in that vasculogenesis and cancer cell growth can be effectively suppressed even at lower doses than with trastuzumab or a VEGF-Trap, and side effects can also be minimised. |
申请公布号 |
WO2012169822(A3) |
申请公布日期 |
2013.03.28 |
申请号 |
WO2012KR04531 |
申请日期 |
2012.06.08 |
申请人 |
KNU-INDUSTRY COOPERATION FOUNDATION;HONG, HYO JEONG;SINGH, ROHIT |
发明人 |
HONG, HYO JEONG;SINGH, ROHIT |
分类号 |
C07K19/00;A61K38/17;A61P35/00;C12N15/62 |
主分类号 |
C07K19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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