发明名称 FUSION PROTEIN FOR SUPPRESSING CANCER CELL GROWTH AND SUPPRESSING VASCULOGENESIS, AND ANTICANCER COMPOSITION COMPRISING SAME
摘要 The present invention relates to a fusion protein resulting from the bonding of a cancer-specific antibody and a vasculogenesis suppressing agent, and relates to a composition for treating cancer comprising same. More specifically, in the present invention it is preferable that the cancer-specific antibody is trastuzumab or a fragment thereof, and the vasculogenesis suppressing agent is a VEGF-Trap. When the fusion protein according to the present invention is used, there are advantages in that vasculogenesis and cancer cell growth can be effectively suppressed even at lower doses than with trastuzumab or a VEGF-Trap, and side effects can also be minimised.
申请公布号 WO2012169822(A3) 申请公布日期 2013.03.28
申请号 WO2012KR04531 申请日期 2012.06.08
申请人 KNU-INDUSTRY COOPERATION FOUNDATION;HONG, HYO JEONG;SINGH, ROHIT 发明人 HONG, HYO JEONG;SINGH, ROHIT
分类号 C07K19/00;A61K38/17;A61P35/00;C12N15/62 主分类号 C07K19/00
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