发明名称 AGONIST DR5 BINDING POLYPEPTIDES
摘要 The present invention relates to amino acid sequences that are directed against TRAIL cell surface receptor 2 (herein also “DR5”), as well as to compounds or constructs thereof, and in particular proteins and polypeptides and nucleotides that encode them (referred to herein in their entirety as “NB agents”) and fragments thereof, and pharmaceutically effective variants thereof, and their use in the diagnosis and treatment of DR5 associated diseases and disorders.
申请公布号 KR20130031241(A) 申请公布日期 2013.03.28
申请号 KR20127023443 申请日期 2011.02.10
申请人 ABLYNX N.V.;NOVARTIS AG 发明人 CROMIE KAREN;DOMBRECHT BRUNO;ETTENBERG SETH;KOLKMAN JOOST;LI JING;MEERSCHAERT KRIS;STOVER DAVID RAYMOND;ZHANG JINGXIN
分类号 C07K16/28;A61K39/395;A61P35/00 主分类号 C07K16/28
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