PREPARATION METHOD OF 1-PALMITOYL-3-ACETYLGLYCEROL, AND PREPARATION METHOD OF 1-PALMITOYL-2-LINOLEOYL-3-ACETYLGLYCEROL USING SAME

摘要

Disclosed are a method for preparing 1-palmitoyl-3-acetylglycerol in a high purity and a high yield without purification by column chromatography, and a method for preparing 1-palmitoyl-2-linoleoyl-3-acetylglycerol in a high purity and a high yield using the same as a core intermediate. The method for preparing 1-palmitoyl-3-acetylglycerol comprises the following steps: reacting 1-palmitoylglycerol represented by chemical formula 2 in the specification, a racemate or an optically active substance, with an acetylating agent to prepare a reaction mixture containing 1-palmitoyl-3-acetylglycerol represented by chemical formula 1 in the specification, a racemate or an optically active substance; and crystallizing the reaction mixture in a C5-C7 saturated hydrocarbon solvent to isolate the optically active 1-palmitoyl-3-acetylglycerol.