ISOLATION AND ENRICHMENT OF NUCLEIC ACIDS ON MICROCHIP

摘要

Methods for isolating, enriching, and/or amplifying target DNA molecules using MEMS-based microdevices are disclosed. The methods can be used for detecting single nucleotide polymorphism, and for isolating and enriching desired DNA molecules, such as aptamers. Further disclosed are detailed descriptions of the method of isolation and detection of amplified target DNA molecules using MEMS-based microdevices.