| 摘要 |
Disclosed herein are pyrrolidine compounds of general formula (I), wherein the substituents are as defined within the specification, processes for their preparation, compositions comprising said compounds and uses thereof. Said compounds are useful as inhibitors of IAP (Inhibitors of Apoptosis), as such are useful in the inducing apoptosis in a cell, for sensitizing a cell to an apoptotic signal, for inhibiting the binding of an IAP protein to a caspase protein, for treating a disease or condition associated with the overexpression of an IAP in a mammal and for treating cancer.
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