ACCURATE QUANTITIATION OF BIOMARKERS IN SAMPLES

摘要

Methods and apparatus for the accurate quantitation of biomarkers in dried blood spots (DBS), including providing a substrate comprising at least one DBS, wherein the DBS comprises at least one biomolecule distributed on the substrate in a gradient pattern; excising at least one sector-shaped sample from the DBS; and assaying the biomolecule in the sector-shaped sample.