| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide simple detection means which exhibits high sensitivity and reproducibility/quantitativity not inferior to those of a fluorescent/chemical luminescence method. <P>SOLUTION: A material detection method is provided which includes a step of generating silver-soluble substances in correlation with the existence or amount of object substances using core-shell metal nanoparticles having a core made of gold nanorods and a shell made of silver and a silver-soluble substance, and detecting the existence and/or amount of the object substances using a change in spectral characteristics due to dissolution of the silver shell as an index. A substrate for an enzyme-linked immunosorbent assay (ELISA) is provided, where core-shell metal nanoparticles having a core made of gold nanorods and a shell made of silver are fixed. <P>COPYRIGHT: (C)2013,JPO&INPIT |
