发明名称 |
ACTIVATABLE FLUOROGENIC COMPOUNDS AND USES THEREOF AS NEAR INFRARED PROBES |
摘要 |
Novel fluorogenic compounds designed such that upon a chemical event, compounds capable of emitting NIR light are generated, are disclosed. The compounds comprise two or more acceptor-containing moieties and a cleavable donor-containing moiety, being in complete pi-electrons conjugation and being such that no delocalization of pi-electrons is enabled. Also disclosed are fluorescent compounds generated upon subjecting the fluorogenic compounds to a chemical event (e.g., deprotonation). Also disclosed are uses of the fluorogenic compounds as NIR probed with a Turn-ON mechanism in monitoring presence and/or level of various analytes. |
申请公布号 |
WO2012123916(A3) |
申请公布日期 |
2013.03.28 |
申请号 |
WO2012IB51255 |
申请日期 |
2012.03.15 |
申请人 |
RAMOT AT TEL-AVIV UNIVERSITY LTD.;SHABAT, DORON;SATCHI-FAINARO, RONIT |
发明人 |
SHABAT, DORON;SATCHI-FAINARO, RONIT |
分类号 |
C09B23/00;A61K49/00;C09B23/08;C09B23/12;G01N33/533;G01N33/58 |
主分类号 |
C09B23/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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